| vaccine | how created | additives |
| DPT | modified Cohen-Wheeler broth | potassium phosphate, sodium chloride, thimerosal (mercury), aluminum |
| DT | diphtheria and tetanus toxoid are detoxified by use of formaldehyde | sodium phosphate, glycine, thimerosal, aluminum |
| DTaP | separating out and removing many of the toxins in the whole B pertussis bacteria and only using a few components of the bacteria; may be detoxified by using formaldehyde | thimerosal, aluminum |
| MMR | measles - weakened
(partially inactivated) live virus derived from Enders’ attenuated Edmonston
strain and grown in cell cultures of chick embryo
mumps - weakened live strain grown in cell cultures of chick embryo rubella - weakened Wistar RA 27/3 strain of live attenuated virus grown in human diploid cell (W-38) culture originating from the tissues of a fetus aborted in 1964 after the mother was infected with rubella |
neomycin, sorbitol and hydrolyzed gelatin |
| LIVE ORAL POLIO VACCINE (OPV) | mixture of three types ofattenuated
(weakened or partially inactivated) polio viruses which have been grown
in African green monkeykidney cell culture. The cells are then grown in
a medium consisting of a salt solution containing amino acids,
antibiotics and calf serum. After
cell growth, the medium is removed and replaced with a medium containing
the virus but no calf serum. |
sorbitol and the antibiotics streptomycin and neomycin |
| INACTIVATED POLIO VACCINE (IPV | three types of polio virus grown in cultures of VERO cells, a continuous line of African green monkey kidney cells | phenoxyethanol and formaldehyde, neomycin, streptomycin and polymyxin |
| HEPATITIS B | genetically engineered; derived from hepatitis B surface antigens produced in yeast cells | 95% hepatitis B virus surface antigen, 4% yeast protein, formaldehyde, aluminum hydroxide and thimerosal |
| VARICELLA ZOSTER (CHICKEN POX) | made from the Oka/Merck strainof live attenuated (weakened) varicella virus. The virus was initially obtained from a child with natural varicella, introduced into human embryonic lung cell cultures, adapted to and propagated in embryonic guinea pig cell cultures and finally propagated in human diploid cell cultures. | sucrose, phosphate, glutamate and processed gelatin |
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